cytotoxicity n : the degree to which something is toxic to living cells
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are a chemical substance or an immune cell.
Cytotoxicity can be measured by the MTT assay, Trypan blue (TB) assay, Sulforhodamine B (SRB) assay, WST assay and clonogenic assay.
Antibody-dependent cell-mediated cytotoxicity (ADCC) describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an antibody. Lymphocyte-mediated cytotoxicity, on the other hand, does not have to be mediated by antibodies; nor does complement-dependent cytotoxicity (CDC), which is mediated by the complement system.
Three groups of cytotoxic lymphocytes are distinguished:
cytotoxicity in German: Zytotoxizität
cytotoxicity in Spanish: Citotoxicidad
cytotoxicity in French: Cytotoxicité
cytotoxicity in Norwegian: Cellegift
cytotoxicity in Russian: Противоопухолевые препараты, цитостатические препараты